Regular Concentration Vitamin B6 50mg / 2ml - 5 vials recommended for kids and adults.
Vitamin B6 is a water-soluble vitamin and is part of the Vitamin B complex group.
The primary role of Vitamin B6 is to act as a coenzyme to many other enzymes in the body that are involved predominantly in metabolism.
This role is performed by the active form of the Vitamin B6, PLP.
Several forms of the Vitamin B6 are known, but pyridoxal phosphate (PLP) is the active form and is a co-factor in many reactions of amino acid metabolism, including transamination, deamination, and decarboxylation.
Vitamin B6 must be obtained from the diet because humans cannot synthesize it,
and the coenzyme, PLP plays a vital role in the function of
approximately 100 enzymes that catalyze essential chemical reactions in
the human body.
The liver is the site for Vitamin B6 metabolism. Vitamin B6 also plays a role in gluconeogenesis.
The classic clinical syndrome for Vitamin B6
deficiency is a seborrhoeic dermatitis-like eruption, atrophic
glossitis with ulceration, angular cheilitis, conjunctivitis,
intertrigo, and neurological symptoms of somnolence, confusion, and
neuropathy.
While severe Vitamin B6
deficiency results in dermatological and neurological changes, less
severe cases present with metabolic lesions associated with insufficient
activities of the co-enzyme PLP .
The
most prominent of the lesions is due to impaired tryptophan-niacin
conversion. This can be detected based on urinary excretion of
xanthurenic acid after an oral tryptophan load.
Vitamin B6 deficiency can also result from impaired transsulfuration of methionine to cysteine. The PLP-dependent transaminases and glycogen phosphorylase provide the vitamin with its role in gluconeogenesis, so deprivation of Vitamin B6 results in impaired glucose tolerance.
A deficiency of Vitamin B6 alone is relatively uncommon and often occurs in association with other Vitamins B complex.
